The family of per- and polyfluoroalkyl substances (PFAS) is facing intense scrutiny. A reporting rule will take effect in the United States in 2026, while Europe has actually been considering a sweeping, cross-industry ban on these substances since early last year. The implications of such a ban on fluoropolymers would be particularly critical, as a discontinuation of these high-performance materials would drastically impact many industries. But what kinds of challenges would emerge in the search for adequate substitutes? This was the focus of a recent study by the Fraunhofer Institute for Mechanics of Materials (IWM) in cooperation with materials experts from the Freudenberg Group.